|Full Name||phosphofructokinase, platelet|
|Product Description||Rabbit Polyclonal antibody to PFK (platelet) (phosphofructokinase, platelet)|
|Background||The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 220.127.116.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM]|
|Synonyms||FLJ40226 antibody, PFK-C antibody, PFKF antibody, PFKP antibody, phosphohexokinase antibody, phosphofructokinase 1 antibody, phosphofructo-1-kinase isozyme C antibody, "Phosphofructokinase, platelet type antibody", 6-phosphofructokinase type C antibody, "6-phosphofructokinase, platelet type antibody", "phosphofructokinase, platelet antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PFK (platelet). The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rabbit, Bovine|
|Predict Reactivity Note||Rat (88%), Rabbit (93%), Bovine (90%)|