|Full Name||6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1|
|Product Description||Rabbit Polyclonal antibody to PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1)|
|Background||This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq]|
|Synonyms||F6PK antibody, HL2K antibody, MGC116715 antibody, MGC116717 antibody, PFRX antibody, PFKFB1 antibody, PFK/FBPase 1 antibody, "fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase antibody", "6PF-2-K/Fru-2,6-P2ase 1 antibody", "6PF-2-K/Fru-2,6-P2ASE liver isozyme antibody", "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PFKFB1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (94%), Xenopus laevis (80%), Pig (98%), Bovine (96%)|