|Full Name||PPARG coactivator 1 beta|
|Product Description||Rabbit Polyclonal antibody to PGC-1 beta (peroxisome proliferator-activated receptor gamma, coactivator 1 beta)|
|Background||The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||PPARG coactivator 1 beta Antibody , PGC1\(beta\) Antibody , ERRL1 Antibody , PGC1B Antibody , PERC Antibody , PPARGC1B Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PGC-1 beta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%)|