|Full Name||peroxisome proliferator-activated receptor gamma, coactivator 1 alpha|
|Product Description||Goat polyclonal antibody to PGC1 alpha|
|Background||The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]|
|Synonyms||PPARGC1 Antibody , LEM6 Antibody , PGC-1(ALPHA) Antibody , PGC1 Antibody , PGC1A Antibody , PGC-1V Antibody , PPARGC1A Antibody|
|Specificity||This antibody is specific for PGC1A.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog|