| Full Name | phosphate regulating endopeptidase homolog, X-linked |
| Background | The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. [provided by RefSeq] |
| Synonyms | HPDR antibody, HPDR1 antibody, HYP antibody, HYP1 antibody, LXHR antibody, PEX antibody, XLH antibody, PHEX antibody, phosphate-regulating neutral endopeptidase antibody, X-linked hypophosphatemia protein antibody, vitamin D-resistant hypophosphatemic rickets protein antibody, "phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) antibody", metalloendopeptidase homolog PEX antibody, "phosphate regulating endopeptidase homolog, X-linked antibody" |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PHEX. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Pig, Chicken, Bovine |
| Predict Reactivity Note | Mouse (96%), Rat (96%), Pig (95%), Chicken (83%), Bovine (95%) |
| Conjugation | Unconjugated |