|Full Name||PHD finger protein 7|
|Product Description||Rabbit Polyclonal antibody to PHF7 (PHD finger protein 7)|
|Background||Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]|
|Synonyms||DKFZp434L1850 antibody, HSPC045 antibody, HSPC226 antibody, MGC26088 antibody, NYD-SP6 antibody, PHF7 antibody, PHD finger protein 7 antibody, testis development protein NYD-SP6 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PHF7. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rat (83%), Rhesus Monkey (99%), Chimpanzee (100%)|