|Full Name||phosphorylase kinase, alpha 1 (muscle)|
|Product Description||Rabbit Polyclonal antibody to PHKA1 (phosphorylase kinase, alpha 1 (muscle))|
|Background||The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 220.127.116.11), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM]|
|Synonyms||MGC132604 antibody, PHKA antibody, PHKA1 antibody, "phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis antibody", phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform antibody, "phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform antibody", phosphorylase kinase alpha M subunit antibody, "phosphorylase kinase, alpha 1 (muscle) antibody"|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human PHKA1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Rhesus Monkey|
|Predict Reactivity Note||Mouse (92%), Rat (92%), Rabbit (96%), Rhesus Monkey (90%)|