|Full Name||paired-like homeobox 2b|
|Product Description||Rabbit polyclonal antibody to PHOX2B (paired-like homeobox 2b)|
|Background||The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq]|
|Synonyms||NBLST2 antibody, NBPhox antibody, PMX2B antibody, PHOX2B antibody, neuroblastoma Phox antibody, neuroblastoma paired-type homeobox protein antibody, paired mesoderm homeobox 2b antibody, paired mesoderm homeobox protein 2B antibody, PHOX2B homeodomain protein antibody, paired-like homeobox 2b antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PHOX2B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis|
|Predict Reactivity Note||Mouse (100%), Xenopus laevis (100%)|