|Full Name||phosphoinositide-3-kinase, regulatory subunit 1 (alpha)|
|Product Description||Rabbit Polyclonal antibody to PI3 kinase p85 alpha (phosphatidylinositol 3-kinase regulatory subunit alpha)|
|Background||Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||GRB1 antibody, p85 antibody, p85-ALPHA antibody, PIK3R1 antibody, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody, "phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody", PI3K regulatory subunit alpha antibody, ptdIns-3-kinase regulatory subunit alpha antibody, phosphatidylinositol 3-kinase-associated p-85 alpha antibody, PI3-kinase subunit p85-alpha antibody, phosphatidylinositol 3-kinase regulatory subunit alpha antibody, "phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human PI3 kinase p85 alpha. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (99%), Zebrafish (86%), Xenopus laevis (88%), Rhesus Monkey (100%), Bovine (100%)|