PI3 kinase p85 alpha antibody
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||84 kDa (note)
|Positive Controls||Jurkat , Raji , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||phosphoinositide-3-kinase, regulatory subunit 1 (alpha)|
|Product Description||Rabbit Polyclonal antibody to PI3 kinase p85 alpha (phosphoinositide-3-kinase, regulatory subunit 1 (alpha))|
|Background||Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||p85 Antibody , PIK3R1 Antibody , phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Antibody , p85-ALPHA Antibody , GRB1 Antibody|
|Target||PI3 kinase p85 alpha|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PI3 kinase p85 alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (89%), Rhesus Monkey (97%), Bovine (93%)|