PI3 kinase p85 alpha antibody [N2C1], Internal
|Applications||IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||84 kDa (note)
|Positive Controls||Jurkat , K562 , THP-1 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||phosphoinositide-3-kinase, regulatory subunit 1 (alpha)|
|Product Description||Rabbit Polyclonal antibody to PI3 kinase p85 alpha (phosphoinositide-3-kinase, regulatory subunit 1 (alpha))|
|Background||Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||GRB1 antibody, p85 antibody, p85-ALPHA antibody, PIK3R1 antibody, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody, "phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody", PI3K regulatory subunit alpha antibody, ptdIns-3-kinase regulatory subunit alpha antibody, phosphatidylinositol 3-kinase-associated p-85 alpha antibody, PI3-kinase subunit p85-alpha antibody, phosphatidylinositol 3-kinase regulatory subunit alpha antibody, "phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PI3 kinase p85 alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (99%), Bovine (94%)|