|Full Name||protein inhibitor of activated STAT, 1|
|Product Description||Rabbit Polyclonal antibody to PIAS1 (protein inhibitor of activated STAT, 1)|
|Background||This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq]|
|Synonyms||DDXBP1 antibody, GBP antibody, GU/RH-II antibody, MGC141878 antibody, MGC141879 antibody, ZMIZ3 antibody, PIAS1 antibody, gu-binding protein antibody, RNA helicase II-binding protein antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 antibody, protein inhibitor of activated STAT protein 1 antibody, "zinc finger, MIZ-type containing 3 antibody", DEAD/H box-binding protein 1 antibody, AR interacting protein antibody, E3 SUMO-protein ligase PIAS1 antibody, protein inhibitor of activated STAT-1 antibody, "protein inhibitor of activated STAT, 1 antibody"|
|Cellular Localization||Nucleus speckle |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PIAS1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (91%), Chicken (96%), Rhesus Monkey (100%), Bovine (100%)|