|Full Name||tumor protein p53 inducible protein 3|
|Product Description||Rabbit polyclonal antibody to PIG3 (tumor protein p53 inducible protein 3)|
|Background||The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||PIG3 antibody, TP53I3 antibody, quinone oxidoreductase homolog antibody, p53-induced gene 3 protein antibody, quinone oxidoreductase PIG3 antibody, tumor protein p53 inducible protein 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PIG3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (97%), Bovine (89%)|