|Full Name||phosphatidylinositol glycan anchor biosynthesis, class A|
|Product Description||Rabbit Polyclonal antibody to PIGA (phosphatidylinositol glycan anchor biosynthesis, class A)|
|Background||This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. [provided by RefSeq]|
|Synonyms||GPI3 antibody, PIG-A antibody, PIGA antibody, phosphatidylinositol N-acetylglucosaminyltransferase subunit A antibody, GPI anchor biosynthesis antibody, GLCNAC-PI synthesis protein antibody, class A GlcNAc-inositol phospholipid assembly protein antibody, "phosphatidylinositol-glycan biosynthesis, class A protein antibody", "phosphatidylinositol glycan anchor biosynthesis, class A antibody"|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PIGA. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Human (100%), Rat (83%), Chicken (80%), Rhesus Monkey (92%)|