PIGR antibody [N2C1], Internal
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||83 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||polymeric immunoglobulin receptor|
|Product Description||Rabbit polyclonal antibody to PIGR (polymeric immunoglobulin receptor)|
|Background||The poly-Ig receptor is expressed on several glandular epithelia including those of liver and breast. It mediates transcellular transport of polymeric immunoglobulin molecules. It is a member of the immunoglobulin superfamily (Hood et al., 1985 [PubMed 3917857]). The receptor has 5 units with homology to the variable (V) units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions.[supplied by OMIM]|
|Synonyms||FLJ22667 antibody, MGC125361 antibody, MGC125362 antibody, PIGR antibody, polymeric immunoglobulin receptor antibody, hepatocellular carcinoma associated protein TB6 antibody, hepatocellular carcinoma-associated protein TB6 antibody, poly-Ig receptor antibody|
|Cellular Localization||Cell membrane; Single-pass type I membrane protein , Secretory component: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PIGR. The exact sequence is proprietary.|