|Full Name||PIN2/TERF1 interacting, telomerase inhibitor 1|
|Product Description||Goat polyclonal antibody to PINX1|
|Background||Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. |
|Synonyms||hepatocellular carcinomarelated putative tumor suppressor, LPTS, 67113 protein, 67-11-3 protein, PIN2-interacting protein 1, hepatocellular carcinoma-related putative tumor suppressor, PINX1, MGC8850, FLJ20565, PIN2interacting protein 1, PIN2interacting protein1, LPTL, PIN2 interacting protein 1|
|Cellular Localization||Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE. |
|Specificity||This antibody is specific for PINX1.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Dog, Bovine|