|Full Name||dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)|
|Product Description||Rabbit polyclonal antibody to PIR1 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting))|
|Background||The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq]|
|Synonyms||PIR1 antibody, DUSP11 antibody, serine/threonine specific protein phosphatase antibody, RNA/RNP complex-1-interacting phosphatase antibody, phosphatase that interacts with RNA/RNP complex 1 antibody, dual specificity protein phosphatase 11 antibody, RNA/RNP complex-interacting phosphatase antibody, dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human PIR1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%)|