|Full Name||protein kinase C, delta|
|Product Description||Rabbit Polyclonal antibody to PKC delta (protein kinase C, delta)|
|Background||Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]|
|Synonyms||MGC49908 antibody, PKCD antibody, nPKC-delta antibody, PRKCD antibody, protein kinase C delta type antibody, protein kinase C delta VIII antibody, "protein kinase C, delta antibody"|
|Cellular Localization||Cytoplasm (By similarity) , Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PKC delta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Dog, Chicken, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (93%), Rat (92%), Dog (92%), Chicken (84%), Bovine (90%)|