|Full Name||protein kinase C, epsilon|
|Product Description||Rabbit Polyclonal antibody to PKC epsilon (protein kinase C, epsilon)|
|Background||Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq]|
|Synonyms||MGC125656 antibody, MGC125657 antibody, PKCE antibody, nPKC-epsilon antibody, PRKCE antibody, protein kinase C epsilon type antibody, "protein kinase C, epsilon antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PKC epsilon. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (97%), Rabbit (98%), Rhesus Monkey (99%), Bovine (99%)|