|Full Name||protein kinase D3|
|Product Description||Rabbit Polyclonal antibody to PKC nu (protein kinase D3)|
|Background||Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq]|
|Synonyms||EPK2 antibody, PKC-NU antibody, PKD3 antibody, PRKCN antibody, nPKC-NU antibody, PRKD3 antibody, "protein kinase C, nu antibody", protein kinase EPK2 antibody, serine/threonine-protein kinase D3 antibody, protein kinase C nu type antibody, protein-serine/threonine kinase antibody, protein kinase D3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PKC nu. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (96%), Rhesus Monkey (99%), Bovine (97%)|