|Full Name||protein kinase C, theta|
|Product Description||Rabbit polyclonal antibody to PKC theta-phospho T219 (protein kinase C, theta)|
|Background||Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq]|
|Synonyms||MGC126514 antibody, MGC141919 antibody, PRKCT antibody, nPKC-theta antibody, PRKCQ antibody, protein kinase C theta type antibody, "protein kinase C, theta antibody", Phospho PKC theta (T219), Phospho PKC theta (pT219), Phospho PKC theta (Thr219), PKC theta (T219), PKC theta (Thr219), PKC theta phospho Phospho, PKC theta phospho pT219, PKC theta (phospho Phospho), PKC theta (phospho pT219)|
|Target||PKC theta-phospho T219|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)|