|Full Name||eukaryotic translation initiation factor 2-alpha kinase 2|
|Product Description||Rabbit Polyclonal antibody to PKR |
|Background||EIF2AK2 is a protein serine/threonine kinase that acquires enzymatic activity following autophosphorylation, a process mediated by double-stranded RNA (dsRNA). Activation of EIF2AK2 allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic protein synthesis initiation factor-2 (EIF2-alpha; MIM 603907), leading to the inhibition of protein synthesis (summary by Kuhen et al., 1996 [PubMed 8812437]).[supplied by OMIM]|
|Synonyms||PRKR Antibody , eukaryotic translation initiation factor 2-alpha kinase 2 Antibody , EIF2AK2 Antibody , EIF2AK1 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PKR. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (82%), Chimpanzee (97%)|