|Full Name||phospholipase C, delta 3|
|Product Description||Rabbit Polyclonal antibody to PLCD3 (phospholipase C, delta 3)|
|Background||This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq]|
|Synonyms||MGC71172 antibody, PLCD3 antibody, PLC delta3 antibody, "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 antibody", PLC-delta-3 antibody, phosphoinositide phospholipase C-delta-3 antibody, phospholipase C-delta-3 antibody, "phospholipase C, delta 3 antibody"|
|Cellular Localization||Membrane; Peripheral membrane protein , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PLCD3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (84%), Rat (82%), Bovine (85%)|