|Full Name||phospholipase C, gamma 2 (phosphatidylinositol-specific)|
|Product Description||Rabbit Polyclonal antibody to PLCG2 (phospholipase C, gamma 2 (phosphatidylinositol-specific))|
|Background||Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1; MIM 172420) and C-gamma-2 enzymes are controlled by receptor tyrosine kinases. The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.[supplied by OMIM]|
|Synonyms||PLCG2 antibody, phospholipase C-IV antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylyinositol-specific) antibody, phospholipase C-gamma-2 antibody, phosphoinositide phospholipase C-gamma-2 antibody, PLC-IV antibody, PLC-gamma-2 antibody, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PLCG2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (95%)|