|Full Name||PMS2 postmeiotic segregation increased 2 (S. cerevisiae)|
|Product Description||Rabbit polyclonal antibody to PMS2 (PMS2 postmeiotic segregation increased 2 (S. cerevisiae))|
|Background||This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]|
|Synonyms||HNPCC4 antibody, PMS2CL antibody, PMSL2 antibody, PMS2 antibody, H_DJ0042M02.9 antibody, mismatch repair endonuclease PMS2 antibody, DNA mismatch repair protein PMS2 antibody, PMS1 protein homolog 2 antibody, PMS2 postmeiotic segregation increased 2 (S. cerevisiae) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PMS2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (88%), Bovine (90%)|