|Full Name||patatin-like phospholipase domain containing 8|
|Product Description||Rabbit Polyclonal antibody to PNPLA8 (patatin-like phospholipase domain containing 8)|
|Background||Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM]|
|Synonyms||IPLA2(GAMMA) antibody, IPLA2-2 antibody, IPLA2G antibody, PNPLA8 antibody, iPLA2 gamma antibody, calcium-independent phospholipase A2-gamma antibody, PNPLA-gamma antibody, patatin-like phospholipase domain-containing protein 8 antibody, intracellular membrane-associated calcium-independent phospholipase A2 gamma antibody, membrane-associated calcium-independent phospholipase A2 gamma antibody, iPLA2-gamma antibody, patatin-like phospholipase domain containing 8 antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity) , Golgi apparatus membrane; Single-pass membrane protein (By similarity) , Cytoplasm , perinuclear region |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PNPLA8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rabbit, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Mouse (92%), Rabbit (94%), Chicken (84%), Rhesus Monkey (98%)|