|Full Name||POM121 membrane glycoprotein|
|Product Description||Rabbit Polyclonal antibody to POM121 (POM121 membrane glycoprotein (rat))|
|Background||The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq]|
|Synonyms||DKFZp586G1822 antibody, DKFZp586P2220 antibody, FLJ41820 antibody, KIAA0618 antibody, MGC3792 antibody, POM121A antibody, POM121 antibody, P145 antibody, pore membrane protein of 121 kDa antibody, nuclear envelope pore membrane protein POM 121 antibody, nuclear envelope pore membrane protein POM 121A antibody, nucleoporin Nup121 antibody, nuclear pore membrane protein 121 kDa antibody, POM121 membrane glycoprotein antibody|
|Cellular Localization||Nucleus , nuclear pore complex , Nucleus membrane; Single-pass membrane protein , Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human POM121. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (81%)|