|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||75 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase|
|Product Description||Rabbit Polyclonal antibody to POMGNT1 (protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase)|
|Background||The protein encoded by this gene is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene.|
|Synonyms||DKFZp761B182 antibody, FLJ20277 antibody, GNTI.2 antibody, MDDGA3 antibody, MDDGB3 antibody, MDDGC3 antibody, MEB antibody, MGAT1.2 antibody, POMGNT1 antibody, "UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2 antibody", "protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 antibody", "protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase antibody"|
|Cellular Localization||Golgi apparatus membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human POMGNT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (84%), Pig (98%), Bovine (99%)|