|Full Name||paraoxonase 2|
|Product Description||Rabbit Polyclonal antibody to PON2 (paraoxonase 2)|
|Background||This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||PON2 antibody, paraoxonase nirs antibody, PON 2 antibody, aromatic esterase 2 antibody, A-esterase 2 antibody, serum aryldialkylphosphatase 2 antibody, serum paraoxonase/arylesterase 2 antibody, paraoxonase 2 antibody|
|Cellular Localization||Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PON2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Sheep, Bovine|
|Predict Reactivity Note||Rat (90%), Dog (91%), Pig (93%), Sheep (91%), Bovine (92%)|