|Full Name||P450 (cytochrome) oxidoreductase|
|Product Description||Rabbit polyclonal antibody to POR (P450 (cytochrome) oxidoreductase)|
|Background||This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]|
|Synonyms||CPR antibody, CYPOR antibody, DKFZp686G04235 antibody, FLJ26468 antibody, P450R antibody, POR antibody, NADPH--cytochrome P450 reductase antibody, NADPH-dependent cytochrome P450 reductase antibody, P450 (cytochrome) oxidoreductase antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Peripheral membrane protein |
|Target||Cytochrome P450 Reductase|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human POR. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Pig, Rabbit, Chicken, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Xenopus laevis (84%), Dog (97%), Pig (96%), Rabbit (96%), Chicken (90%), Rhesus Monkey (100%), Bovine (94%), Guinea pig (96%)|