|Full Name||protection of telomeres 1 homolog (S. pombe)|
|Product Description||Rabbit Polyclonal antibody to POT1 (POT1 protection of telomeres 1 homolog (S. pombe))|
|Background||This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq]|
|Synonyms||DKFZp586D211 antibody, HPOT1 antibody, POT1 antibody, protection of telomeres protein 1 antibody, POT1-like telomere end-binding protein antibody, protection of telomeres 1 homolog (S. pombe) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human POT1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (87%)|