|Full Name||peroxisome proliferator-activated receptor alpha|
|Product Description||Rabbit Polyclonal antibody to PPAR alpha (peroxisome proliferator-activated receptor alpha)|
|Background||Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq]|
|Synonyms||MGC2237 antibody, MGC2452 antibody, NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, PPARA antibody, peroxisome proliferator-activated receptor alpha antibody, PPAR-alpha antibody, peroxisome proliferator-activated nuclear receptor alpha variant 3 antibody, nuclear receptor subfamily 1 group C member 1 antibody, "peroxisome proliferative activated receptor, alpha antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human PPAR alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat, Queen Bee, Honeybee|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Dog (91%), Pig (92%), Rhesus Monkey (98%), Bovine (88%), Guinea pig (87%)|