PPM1B antibody [N1C1]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||53 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||protein phosphatase, Mg2+/Mn2+ dependent, 1B|
|Product Description||Rabbit Polyclonal antibody to PPM1B (protein phosphatase, Mg2+/Mn2+ dependent, 1B)|
|Background||The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]|
|Synonyms||MGC21657 antibody, PP2C-beta-X antibody, PP2CB antibody, PP2CBETA antibody, PPC2BETAX antibody, PPM1B antibody, "protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform antibody", PP2C-beta antibody, protein phosphatase 1B antibody, protein phosphatase 2C isoform beta antibody, protein phosphatase 2C-like protein antibody, "protein phosphatase, Mg2+/Mn2+ dependent, 1B antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPM1B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (94%), Rat (96%), Xenopus laevis (89%), Chicken (96%), Rhesus Monkey (100%), Bovine (98%)|