|Full Name||protein phosphatase 1, catalytic subunit, alpha isozyme|
|Product Description||Rabbit Polyclonal antibody to PPP1A (protein phosphatase 1, catalytic subunit, alpha isozyme)|
|Background||The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC15877 antibody, MGC1674 antibody, PP-1A antibody, PP1alpha antibody, PPP1A antibody, PPP1CA antibody, serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit antibody, "protein phosphatase 1, catalytic subunit, alpha isoform antibody", serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody, "protein phosphatase 1, catalytic subunit, alpha isozyme antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP1A. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Dog, Pig, Rabbit, Bovine|
|Predict Reactivity Note||Mouse (99%), Xenopus laevis (97%), Dog (100%), Pig (100%), Rabbit (97%), Bovine (100%)|