|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||protein phosphatase 1, catalytic subunit, beta isozyme|
|Product Description||Rabbit Polyclonal antibody to PPP1CB (protein phosphatase 1, catalytic subunit, beta isozyme)|
|Background||The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]|
|Synonyms||MGC3672 antibody, PP-1B antibody, PP1beta antibody, PPP1CD antibody, PPP1CB antibody, protein phosphatase 1-beta antibody, protein phosphatase 1-delta antibody, "protein phosphatase 1, catalytic subunit, delta isoform antibody", serine/threonine protein phosphatase PP1-beta catalytic subunit antibody, "protein phosphatase 1, catalytic subunit, beta isoform antibody", serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, "protein phosphatase 1, catalytic subunit, beta isozyme antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP1CB. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Dog, Pig, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (99%), Xenopus laevis (100%), Dog (99%), Pig (100%), Rabbit (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)|