|Full Name||protein phosphatase 2, regulatory subunit A, beta|
|Product Description||Rabbit polyclonal antibody to PPP2R1B (protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform)|
|Background||This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC26454 antibody, PP2A-Abeta antibody, PR65B antibody, PPP2R1B antibody, "PP2A, subunit A, PR65-beta isoform antibody", serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform antibody, "protein phosphatase 2, structural/regulatory subunit A, beta antibody", "PP2A, subunit A, R1-beta isoform antibody", "protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform antibody", "protein phosphatase 2, regulatory subunit A, beta antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP2R1B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Xenopus laevis, Chimpanzee|
|Predict Reactivity Note||Human (100%), Mouse (94%), Rat (94%), Zebrafish (87%), Xenopus laevis (86%), Chimpanzee (99%)|