|Full Name||protein phosphatase 2A activator, regulatory subunit 4|
|Product Description||Rabbit Polyclonal antibody to PPP2R4 (protein phosphatase 2A activator, regulatory subunit 4)|
|Background||Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||MGC2184 antibody, PP2A antibody, PR53 antibody, PTPA antibody, PPP2R4 antibody, PP2A subunit B' isoform PR53 antibody, phosphotyrosyl phosphatase activator antibody, serine/threonine-protein phosphatase 2A activator antibody, PP2A phosphatase activator antibody, serine/threonine-protein phosphatase 2A regulatory subunit B' antibody, "protein phosphatase 2A, regulatory subunit B' (PR 53) antibody", "protein phosphatase 2A activator, regulatory subunit 4 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (94%), Rabbit (96%)|