|Full Name||protein phosphatase 3, catalytic subunit, gamma isozyme|
|Product Description||Rabbit polyclonal antibody to PPP3CC (protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform)|
|Background||Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]|
|Synonyms||CALNA3 antibody, CNA3 antibody, PP2Bgamma antibody, PPP3CC antibody, "calcineurin, testis-specific catalytic subunit antibody", calmodulin-dependent calcineurin A subunit gamma isoform antibody, "protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform antibody", "protein phosphatase 2B, catalytic subunit, gamma isoform antibody", serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform antibody, CAM-PRP catalytic subunit antibody, "protein phosphatase 3, catalytic subunit, gamma isozyme antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP3CC. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Bovine (97%)|