|Full Name||protein phosphatase 4, regulatory subunit 2|
|Product Description||Rabbit Polyclonal antibody to PPP4R2 (serine/threonine-protein phosphatase 4 regulatory subunit 2)|
|Background||Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. |
|Synonyms||MGC131930 antibody, PP4R2 antibody, PPP4R2 antibody, serine/threonine-protein phosphatase 4 regulatory subunit 2 antibody, "protein phosphatase 4, regulatory subunit 2 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPP4R2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Chicken|
|Predict Reactivity Note||Mouse (80%), Xenopus laevis (80%), Chicken (86%)|