|Full Name||palmitoyl-protein thioesterase 1|
|Product Description||Rabbit polyclonal antibody to PPT1 (palmitoyl-protein thioesterase 1)|
|Background||The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||CLN1 antibody, INCL antibody, PPT antibody, PPT1 antibody, PPT-1 antibody, ceroid-palmitoyl-palmitoyl-protein thioesterase 1 antibody, palmitoyl-protein thioesterase 1 antibody, palmitoyl-protein hydrolase 1 antibody|
|Cellular Localization||Lysosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PPT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (94%), Rhesus Monkey (99%), Bovine (93%)|