|Full Name||mitogen-activated protein kinase-activated protein kinase 5|
|Product Description||Rabbit Polyclonal antibody to PRAK (mitogen-activated protein kinase-activated protein kinase 5)|
|Background||The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||PRAK antibody, MAPKAPK5 antibody, MAPK-activated protein kinase 5 antibody, MAPKAP kinase 5 antibody, MAP kinase-activated protein kinase 5 antibody, MAPKAPK-5 antibody, p38-regulated/activated protein kinase antibody, mitogen-activated protein kinase-activated protein kinase 5 antibody|
|Cellular Localization||Cytoplasm (Probable) , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PRAK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (96%), Zebrafish (92%), Pig (98%), Chicken (95%), Rhesus Monkey (99%), Bovine (96%)|