PRAK antibody [N3C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||54 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||mitogen-activated protein kinase-activated protein kinase 5|
|Product Description||Rabbit polyclonal antibody to PRAK (mitogen-activated protein kinase-activated protein kinase 5)|
|Background||The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||PRAK antibody, MAPKAPK5 antibody, MAPK-activated protein kinase 5 antibody, MAPKAP kinase 5 antibody, MAP kinase-activated protein kinase 5 antibody, MAPKAPK-5 antibody, p38-regulated/activated protein kinase antibody, mitogen-activated protein kinase-activated protein kinase 5 antibody|
|Cellular Localization||Cytoplasm (Probable) , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PRAK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Zebrafish (82%), Pig (97%), Chicken (95%), Rhesus Monkey (100%), Bovine (97%)|