|Full Name||preferentially expressed antigen in melanoma|
|Product Description||Rabbit Polyclonal antibody to PRAME (preferentially expressed antigen in melanoma)|
|Background||This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq]|
|Synonyms||CT130 antibody, MAPE antibody, OIP4 antibody, PRAME antibody, cancer/testis antigen 130 antibody, OIP-4 antibody, opa-interacting protein 4 antibody, Opa-interacting protein OIP4 antibody, preferentially expressed antigen of melanoma antibody, melanoma antigen preferentially expressed in tumors antibody, preferentially expressed antigen in melanoma antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PRAME. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (96%)|