|Full Name||AKT1 substrate 1 (proline-rich)|
|Product Description||Rabbit Polyclonal antibody to PRAS40 (AKT1 substrate 1 (proline-rich))|
|Background||AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM]|
|Synonyms||Lobe antibody, MGC2865 antibody, PRAS40 antibody, AKT1S1 antibody, proline-rich AKT1 substrate 1 antibody, 40 kDa proline-rich AKT substrate antibody, "proline-rich Akt substrate, 40 kDa antibody", AKT1 substrate 1 (proline-rich) antibody|
|Cellular Localization||Cytoplasm , cytosol |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PRAS40. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (87%), Chimpanzee (99%), Bovine (90%)|