| Full Name | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
| Background | The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq] |
| Synonyms | KIAA1415 antibody, P-REX1 antibody, PREX1 antibody, ptdIns(3,4,5)-dependent Rac exchanger 1 antibody, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antibody |
| Cellular Localization | Cytoplasm , cytosol , Cell membrane |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PREX1. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |