| Full Name | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
| Background | The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008] |
| Synonyms | P REX1 Antibody |
| Cellular Localization | Mainly cytosolic. Some amount is apparently associated to the plasma membrane. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Peptide with sequence C-ERSNLPTDASTTA, from the internal region of the protein sequence according to NP_065871.2. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Dog, Bovine |
| Conjugation | Unconjugated |