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1 .GTX88346 PREX1 antibody, Internal

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PREX1 antibody, Internal


  • Host / ClonalityGoat Polyclonal
  • ApplicationsWB
  • Species reactivityHuman
Cat No: GTX88346
Package Price Qty
100 μgUSD 319.00
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  • Anti-PREX1 antibody, Internal used in Western Blot (WB). GTX88346
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  • Datasheet

  • Application Information: PREX1 antibody, Internal

Catalog Number GTX88346
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Product Name PREX1 antibody, Internal
See all PREX1 products
ApplicationsWB
Application NoteApprox 150kDa band observed in Human Brain (Temporal Cortex) lysates (calculated MW of 186kDa according to NP_065871.2). Recommended concentration: 1-3µg/ml.
Form SuppliedLiquid
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Specifications: PREX1 antibody, Internal

Full Namephosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Product DescriptionGoat polyclonal antibody to PREX1
BackgroundFunctions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Synonymsphosphatidylinositol3,4,5trisphosphatedependent Rac exchanger, OTTHUMP00000031228, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger, phosphatidylinositol3,4,5trisphosphatedependent Rac exchange factor1, P-REX1, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1, PREX1, phosphatidylinositol3,4,5trisphosphatedependent Rac exchanger1, KIAA1415, phosphatidylinositol 3,4,5trisphosphatedependent Rac exchanger 1, P REX1
Cellular LocalizationMainly cytosolic. Some amount is apparently associated to the plasma membrane.
SpecificityThis antibody is specific for PREX1.
HostGoat
ClonalityPolyclonal
IsotypeIgG
ImmunogenC-ERSNLPTDASTTA
Antigen SpeciesHuman
Species ReactivityHuman
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
 		Mouse, Rat, Dog, Bovine
ConjugationUnconjugated

  • Storage Conditions: PREX1 antibody, Internal

Storage BufferTris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction Aliquot and store at -20°C. Minimize freezing and thawing.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Apoptosis > Induction > Extracellular signals
  • Cell Biology > Apoptosis > Induction from extracellular signals
  • Disease Related > Diabetes
  • Immunology > Autoimmunity > Autoimmune diseases > Diabetes
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PREX1 antibody, Internal validated data
  • Anti-PREX1 antibody, Internal used in Western Blot (WB). GTX88346
    • GTX88346 WB Image
      GTX88346 (1µg/ml) staining of Human Temporal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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  • Anti-PREX1 antibody, Internal used in Western Blot (WB). GTX88346
    • GTX88346 WB Image
      GTX88346 (1µg/ml) staining of Human Temporal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
      Top
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