PRP8 antibody [C3-2], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||274 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)|
|Product Description||Rabbit polyclonal antibody to PRP8 (PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae))|
|Background||Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq]|
|Synonyms||HPRP8 antibody, PRP8 antibody, PRPC8 antibody, RP13 antibody, PRPF8 antibody, splicing factor Prp8 antibody, "U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p antibody", PRP8 homolog antibody, p220 antibody, precursor mRNA processing protein antibody, apoptosis-regulated protein 1 antibody, apoptosis-regulated protein 2 antibody, pre-mRNA-processing-splicing factor 8 antibody, 220 kDa U5 snRNP-specific protein antibody, PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) antibody|
|Cellular Localization||Nucleus speckle |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRP8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Bovine (100%)|