|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||35 kDa (note)
|Positive Controls||293T , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||phosphoribosyl pyrophosphate synthetase 1|
|Product Description||Rabbit Polyclonal antibody to PRPS1 (phosphoribosyl pyrophosphate synthetase 1)|
|Background||This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. [provided by RefSeq]|
|Synonyms||ARTS antibody, CMTX5 antibody, DFN2 antibody, DFNX1 antibody, KIAA0967 antibody, PPRibP antibody, PRSI antibody, PRPS1 antibody, dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1) antibody, "deafness, X-linked 2, perceptive, congenital antibody", "deafness 2, perceptive, congenital antibody", ribose-phosphate diphosphokinase 1 antibody, phosphoribosyl pyrophosphate synthase I antibody, ribose-phosphate pyrophosphokinase 1 antibody, phosphoribosyl pyrophosphate synthetase 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PRPS1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Xenopus laevis (95%), Rhesus Monkey (100%), Bovine (100%)|