PRX III antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||28 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||peroxiredoxin 3|
|Product Description||Rabbit Polyclonal antibody to Peroxiredoxin 3 (peroxiredoxin 3)|
|Background||This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||AOP-1 antibody, AOP1 antibody, MER5 antibody, MGC104387 antibody, MGC24293 antibody, PRO1748 antibody, SP-22 antibody, PRDX3 antibody, antioxidant protein 1 antibody, peroxiredoxin-3 antibody, "thioredoxin-dependent peroxide reductase, mitochondrial antibody", peroxiredoxin III antibody, protein MER5 homolog antibody, peroxiredoxin 3 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Peroxiredoxin 3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rhesus Monkey|
|Predict Reactivity Note||Mouse (86%), Rat (86%), Dog (86%), Rhesus Monkey (93%)|