|Full Name||kallikrein-related peptidase 3|
|Product Description||Rabbit polyclonal antibody to PSA (kallikrein-related peptidase 3)|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]|
|Synonyms||APS antibody, KLK2A1 antibody, PSA antibody, hK3 antibody, KLK3 antibody, P-30 antigen antibody, prostate specific antigen antibody, seminin antibody, prostate-specific antigen antibody, kallikrein-3 antibody, gamma-seminoprotein antibody, semenogelase antibody, kallikrein-related peptidase 3 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PSA. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rhesus Monkey|
|Predict Reactivity Note||Human (100%), Rhesus Monkey (88%)|